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CS-W001157 4
Total: USD 88.00

3-Carboxy-6-hydroxycoumarin

  • CAS No. 56437-16-2

  • Cat. No. CS-0047583
  • Purity≥95%
  • MDL No.MFCD16295011

*For research and further manufacturing use only, not for direct human use.

3-Carboxy-6-hydroxycoumarin|CS-0047583

Structure of 56437-16-2

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General Information

  • CAS No. 56437-16-2
  • Cat. No. CS-0047583
  • Purity ≥95%
  • MDL No. MFCD16295011
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₆O₅
  • Molecular Weight 206.15
  • Synonym(s) None
  • SMILES O=C(C1=CC2=CC(O)=CC=C2OC1=O)O

Description

3-Carboxy-6-hydroxycoumarin delivers a dual functional handle—carboxylic acid and phenolic hydroxyl—enabling straightforward conjugation in bioconjugation and probe design. This bench-stable scaffold integrates readily into fluorescent probes, leveraging its inherent electron-rich core for enhanced photophysical performance.

Application

3-Carboxy-6-hydroxycoumarin serves as a versatile building block for functionalized coumarin scaffolds, enabling straightforward derivatization at both the carboxylic acid and phenolic hydroxyl groups. Its dual functionality facilitates conjugation, metal chelation, and incorporation into bioactive molecules. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for synthetic workflows requiring precise structural control in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   87.74
  • LogP   1.1968
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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