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Structure of 5638-60-8
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1,4-Oxazepane is a seven-membered heterocyclic compound featuring oxygen and nitrogen atoms at positions 1 and 4. This scaffold exhibits enhanced metabolic stability compared to smaller analogs, enabling its use in bioactive molecule design. The ring’s conformational flexibility supports diverse molecular interactions, making it valuable in medicinal chemistry applications where modulated solubility and target engagement are critical.
1,4-Oxazepane serves as a versatile heterocyclic scaffold in medicinal chemistry, offering a balanced combination of metabolic stability and hydrogen-bonding capacity. Its seven-membered ring with nitrogen and oxygen atoms enables predictable conformational behavior and facilitates incorporation into bioactive molecules. The ring functions as a key building block for modulating solubility and target engagement in drug discovery programs. It exhibits robust bench stability and compatibility with standard synthetic transformations, including reductive amination and functional group interconversions.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H318-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P271-P280-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362+P364-P370+P378-P403+P233-P403+P235-P405-P501
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Lot numbers can be found on the outside label of a product: