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CS-W001157 4
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2-Bromothiophene-3-carbonitrile

  • CAS No. 56182-43-5

  • Cat. No. CS-0096797
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Bromothiophene-3-carbonitrile|CS-0096797

Structure of 56182-43-5

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General Information

  • CAS No. 56182-43-5
  • Cat. No. CS-0096797
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂BrNS
  • Molecular Weight 188.05
  • Synonym(s) 3-Thiophenecarbonitrile, 2-bromo-
  • SMILES N#CC1=C(Br)SC=C1

Description

2-Bromothiophene-3-carbonitrile features a brominated thiophene core paired with a nitrile group, enabling direct incorporation into cross-coupling reactions. This electron-deficient heterocycle offers enhanced reactivity in palladium-catalyzed transformations and serves as a key building block for functionalized thienyl scaffolds in pharmaceutical and materials chemistry.

Application

2-Bromothiophene-3-carbonitrile serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine and nitrile functionalities. The molecule exhibits excellent bench stability and compatibility with standard reaction conditions, facilitating efficient incorporation into complex scaffolds for medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   23.79
  • LogP   2.38228
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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