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CS-W001157 4
Total: USD 88.00

Methyl 6-(hydroxymethyl)nicotinate

  • CAS No. 56026-36-9

  • Cat. No. CS-W002650
  • Purity≥95%
  • MDL No.MFCD00643821

*For research and further manufacturing use only, not for direct human use.

Methyl 6-(hydroxymethyl)nicotinate|CS-W002650

Structure of 56026-36-9

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General Information

  • CAS No. 56026-36-9
  • Cat. No. CS-W002650
  • Purity ≥95%
  • MDL No. MFCD00643821
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃
  • Molecular Weight 167.16
  • Synonym(s) None
  • SMILES COC(C1=CN=C(CO)C=C1)=O

Description

Methyl 6-(hydroxymethyl)nicotinate features a pyridine ring with strategically positioned ester and hydroxymethyl groups, enabling direct incorporation into bioactive molecule scaffolds. The hydroxymethyl functionality offers a handle for selective derivatization under mild conditions, while the ester group enhances solubility and stability in organic media. This compound serves as a key building block for NAD+ analogs and related redox cofactor systems.

Application

Methyl 6-(hydroxymethyl)nicotinate serves as a versatile building block in synthetic organic chemistry, enabling straightforward functionalization at the pyridine ring’s C6 position. The pendant hydroxymethyl group facilitates oxidation to carboxylic acid, reduction to alcohol, or ether formation, while the methyl ester supports standard transformations such as hydrolysis or coupling reactions. Its bench-stable nature and compatibility with common protecting group strategies make it a practical choice for constructing heterocyclic scaffolds relevant to medicinal chemistry and agrochemical development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   0.3605
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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