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CS-W001157 4
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Methyl 5-formylpicolinate

  • CAS No. 55876-91-0

  • Cat. No. CS-0054096
  • Purity≥96%
  • MDL No.MFCD11100669

*For research and further manufacturing use only, not for direct human use.

Methyl 5-formylpicolinate|CS-0054096

Structure of 55876-91-0

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General Information

  • CAS No. 55876-91-0
  • Cat. No. CS-0054096
  • Purity ≥96%
  • MDL No. MFCD11100669
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO₃
  • Molecular Weight None
  • Synonym(s) Methyl 5-formylpyridine-2-carboxylate
  • SMILES O=C(C1=NC=C(C=O)C=C1)OC

Description

Methyl 5-formylpicolinate is a versatile heterocyclic ester featuring a formyl group at the 5-position of the picolinate ring. This electrophilic aldehyde moiety enables direct conjugation in transition-metal-catalyzed couplings and facilitates downstream functionalization in synthetic sequences. The molecule exhibits excellent solubility in common organic solvents and stability under standard bench conditions, making it suitable for use in medicinal chemistry and materials synthesis workflows.

Application

Methyl 5-formylpicolinate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to heterocyclic scaffolds and functionalized aromatic systems. The aldehyde group facilitates nucleophilic additions, reductive aminations, and condensation reactions, while the ester functionality supports selective transformations under mild conditions. Its bench-stable nature and compatibility with common protecting group strategies make it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   56.26
  • LogP   0.6807
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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