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Structure of 39977-41-8
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5-(Hydroxymethyl)picolinic acid features a pyridine ring bearing both carboxylic acid and hydroxymethyl groups at positions 2 and 5, respectively. This configuration enables direct conjugation to biomolecules via the hydroxymethyl moiety while maintaining solubility and stability under standard bench conditions. The molecule integrates readily into bioconjugation workflows requiring polar, functionalized linkers.
5-(Hydroxymethyl)picolinic acid serves as a versatile building block for heterocyclic synthesis and bioactive molecule development. Its pyridine ring provides a stable scaffold for functionalization, while the pendant hydroxymethyl group enables selective oxidation, etherification, or coupling reactions. The carboxylic acid moiety facilitates amide bond formation and salt crystallization, enhancing solubility and purification. This compound exhibits good bench stability and compatibility with standard synthetic protocols, making it valuable in medicinal chemistry and process R&D workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: