Lot numbers can be found on the outside label of a product:
6-Bromo-2-hydroxyquinoxaline
-
CAS No. 55687-34-8
- Cat. No. CS-W005675
- Purity≥95%
- MDL No.MFCD10566852
*For research and further manufacturing use only, not for direct human use.
Structure of 55687-34-8
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 55687-34-8
- Cat. No. CS-W005675
- Purity ≥95%
- MDL No. MFCD10566852
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₅BrN₂O
- Molecular Weight 225.04
- Synonym(s) 6-Bromoquinoxalin-2(1H)-one
- SMILES BrC2=CC=C1N=C(C=NC1=C2)O
Description
6-Bromo-2-hydroxyquinoxaline features a brominated quinoxaline core with a hydroxyl group at the 2-position, enabling direct functionalization in cross-coupling and metal-ligand coordination. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and fluorescent probes, offering enhanced solubility and stability under standard conditions.
Application
6-Bromo-2-hydroxyquinoxaline serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization at the C2 position via palladium-catalyzed cross-coupling reactions. The bromo group facilitates Suzuki, Stille, or Negishi coupling, while the phenolic hydroxyl supports derivatization or metal complexation. Its stability under standard reaction conditions and compatibility with diverse protecting groups make it ideal for modular synthesis of quinoxaline-based scaffolds in API development and functional molecular design.
Synthesis
-
Route1
-
96089-46-2 - ~86%
-
In-stock
55687-34-8
References
-
WO2009/39134 A1, ; Page/Page column 185 ;
-
-
Route2
-
In-stock
1196-57-2 - ~39%
-
In-stock
55687-34-8
References
-
WO2010/136755 A1, ; Page/Page column 46; 47 ; WO 2010/136755 A1
-
-
Route3
-
98416-75-2
- ~%
-
In-stock
55687-34-8
References
-
Heterocycles, , vol. 23, # 1 p. 143 - 151
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 46.01
- LogP 2.0979
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 6-Bromo-2-hydroxyquinoxaline sigma6-Bromo-2-hydroxyquinoxaline manufacturer6-Bromo-2-hydroxyquinoxaline price6-Bromo-2-hydroxyquinoxaline structure6-Bromo-2-hydroxyquinoxaline SDSbuy 6-Bromo-2-hydroxyquinoxaline6-Bromo-2-hydroxyquinoxaline supplier6-Bromo-2-hydroxyquinoxaline uses6-Bromo-2-hydroxyquinoxaline molecular weightprice of 6-Bromo-2-hydroxyquinoxaline6-Bromo-2-hydroxyquinoxaline chemical name formula of 6-Bromo-2-hydroxyquinoxaline