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CS-W001157 4
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6-Bromo-2-chloroquinoxaline

  • CAS No. 55687-02-0

  • Cat. No. CS-W006016
  • Purity≥95%
  • MDL No.MFCD09260998

*For research and further manufacturing use only, not for direct human use.

6-Bromo-2-chloroquinoxaline|CS-W006016

Structure of 55687-02-0

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General Information

  • CAS No. 55687-02-0
  • Cat. No. CS-W006016
  • Purity ≥95%
  • MDL No. MFCD09260998
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄BrClN₂
  • Molecular Weight 243.49
  • Synonym(s) None
  • SMILES BrC2=CC=C1N=C(C=NC1=C2)Cl

Description

6-Bromo-2-chloroquinoxaline is a heterocyclic halogenated quinoxaline featuring bromine at the 6-position and chlorine at the 2-position. This electron-deficient scaffold enables direct coupling in Pd-catalyzed cross-coupling reactions, offering high reactivity and compatibility with diverse functional groups under standard conditions.

Application

6-Bromo-2-chloroquinoxaline serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The bromo and chloro substituents offer orthogonal functionalization potential, facilitating sequential derivatization. Its stability under standard reaction conditions and ease of purification make it well-suited for medicinal chemistry campaigns and the construction of complex quinoxaline-based scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   3.0457
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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