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Structure of 5521-39-1
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This piperazine-based scaffold integrates a para-aminophenyl moiety with a terminal hydroxylethyl group, enabling versatile conjugation and solubility enhancement in medicinal chemistry applications. The amine functionality supports derivatization, while the hydroxyl group facilitates hydrogen bonding and improved aqueous compatibility.
2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol serves as a versatile bifunctional building block in medicinal chemistry, enabling the construction of diverse heterocyclic scaffolds. Its piperazine core provides enhanced solubility and metabolic stability, while the primary amine and hydroxyl groups offer orthogonal handles for conjugation and derivatization. The molecule exhibits excellent bench stability and compatibility with standard coupling protocols, facilitating efficient synthesis of targeted bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: