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CS-W001157 4
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N-(5-Bromo-1,3,4-thiadiazol-2-yl)acetamide

  • CAS No. 55114-97-1

  • Cat. No. CS-0153954
  • Molecule weight222.06
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-(5-Bromo-1,3,4-thiadiazol-2-yl)acetamide|CS-0153954

Structure of 55114-97-1

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General Information

  • CAS No. 55114-97-1
  • Cat. No. CS-0153954
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄BrN₃OS
  • Molecular Weight 222.06
  • Synonym(s) None
  • SMILES CC(NC1=NN=C(S1)Br)=O

Description

N-(5-Bromo-1,3,4-thiadiazol-2-yl)acetamide features a brominated 1,3,4-thiadiazole core paired with an acetyl amide handle, enabling direct integration into bioconjugation workflows. The electron-deficient heterocycle enhances reactivity in nucleophilic substitution processes, while the acetamide group provides solubility and stability under standard conditions. This compound serves as a robust scaffold for medicinal chemistry and materials synthesis.

Application

N-(5-Bromo-1,3,4-thiadiazol-2-yl)acetamide serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. The bromo-substituted thiadiazole core enables efficient cross-coupling reactions, while the acetamide group offers moderate stability and facilitates purification. Its functional group tolerance supports downstream derivatization in API development, particularly for bioactive scaffolds requiring halogenated heterocycles.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

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Computational Chemistry Data

  • TPSA   54.88
  • LogP   1.259
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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