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Structure of 5454-06-8
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This malonate derivative features a phenylpropyl side chain that enhances hydrophobicity and steric bulk, enabling efficient incorporation into complex molecular scaffolds. The conjugated diacid system supports robust condensation reactions under standard conditions, facilitating the synthesis of substituted cyclopropanes and heterocycles in medicinal chemistry workflows.
2-(3-Phenylpropyl)propanedioic acid serves as a versatile building block for the synthesis of substituted malonic acid derivatives and heterocyclic scaffolds. Its benzylic substitution pattern enhances stability and facilitates functional group manipulations, while the flanking carboxylic acid groups enable decarboxylation, esterification, and Claisen-type condensations. The molecule functions effectively in standard synthetic workflows requiring controlled carbon chain extension and aromatic integration.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: