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CS-W001157 4
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Pyrazolo[1,5-a][1,3,5]triazin-4(3H)-one

  • CAS No. 54346-27-9

  • Cat. No. CS-W022939
  • Purity≥95%
  • MDL No.MFCD20617746

*For research and further manufacturing use only, not for direct human use.

Pyrazolo[1,5-a][1,3,5]triazin-4(3H)-one|CS-W022939

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General Information

  • CAS No. 54346-27-9
  • Cat. No. CS-W022939
  • Purity ≥95%
  • MDL No. MFCD20617746
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄N₄O
  • Molecular Weight 136.11
  • Synonym(s) Pyrazolo[1,5-a][1,3,5]triazin-4(1H)-one
  • SMILES O=C1NC=NC2=CC=NN21

Description

Pyrazolo[1,5-a][1,3,5]triazin-4(3H)-one delivers a rigid, electron-deficient heterocyclic scaffold ideal for bioactive compound design. This bench-stable core integrates readily into pharmaceutical intermediates, offering enhanced solubility and predictable reactivity in synthetic transformations.

Application

Pyrazolo[1,5-a][1,3,5]triazin-4(3H)-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its fused ring system exhibits robust bench stability and tolerates diverse functional groups, facilitating downstream modifications via nucleophilic substitution or transition-metal-catalyzed coupling. The core structure functions as a privileged motif in kinase inhibitors and other pharmaceutical candidates, with predictable reactivity in standard synthetic protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.05
  • LogP   -0.5824
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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