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CS-W001157 4
Total: USD 88.00

4-Pyridinecarbamic acid, ethyl ester

  • CAS No. 54287-92-2

  • Cat. No. CS-0028344
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Pyridinecarbamic acid, ethyl ester|CS-0028344

Structure of 54287-92-2

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General Information

  • CAS No. 54287-92-2
  • Cat. No. CS-0028344
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂
  • Molecular Weight 166.18
  • Synonym(s) Ethyl pyridin-4-ylcarbamate
  • SMILES CCOC(NC1=CC=NC=C1)=O

Description

Ethyl 4-pyridylcarbamate features a pyridyl nitrogen that enables coordination in metal-ligand systems, while the ethyl carbamate moiety offers stability and ease of functionalization. This combination supports its use in synthesizing bioactive heterocycles and advanced ligands for catalysis.

Application

Ethyl 4-pyridylcarbamate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to pyridine-containing scaffolds. Its dual functionality—pyridyl nitrogen and carbamate ester—facilitates selective functionalization, including palladium-catalyzed cross-coupling reactions and controlled hydrolysis. The compound exhibits excellent bench stability and ease of purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1
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      504-24-5
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      541-41-3
    • ~88%
    • In-stock
      4-Pyridinecarbamic acid, ethyl ester|CS-0028344
      54287-92-2

    References

    • PURDUE RESEARCH FOUNDATION Patent: WO2007/61554 A2, 2007 ; Location in patent: Page/Page column 12 ;
  • Route2
    • null|null
      504-24-5
    • null|null
      1336-21-6
    • null|null
      541-41-3
    • ~%
    • In-stock
      4-Pyridinecarbamic acid, ethyl ester|CS-0028344
      54287-92-2

    References

    • Schering Corporation Patent: US5891872 A1, 1999 ;
  • Route3
    • null|null
      504-24-5
    • null|null
      3278-35-1
    • ~%
    • In-stock
      4-Pyridinecarbamic acid, ethyl ester|CS-0028344
      54287-92-2

    References

    • Martin, Arnim A.; Zeuner, Frank; Barnikow, Guenter Zeitschrift fuer Chemie (Stuttgart, Germany), 1990 , vol. 30, # 3 p. 90 - 91

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   51.22
  • LogP   1.65
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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