tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate

Name: tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 167081-37-0
Cat. No. CS-0047940
Purity≥98%
MDL No.MFCD08166748

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate|CS-0047940

Structure of 167081-37-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 167081-37-0
Cat. No. CS-0047940
Purity ≥98%
MDL No. MFCD08166748
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₉NO₃
Molecular Weight 201.26
Synonym(s) trans-1-(Boc-amino)-3-(hydroxymethyl)cyclobutane - SB7652
SMILES CC(C)(C)OC(=O)N[C@H]1C[C@H](CO)C1

Description

tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate features a rigid trans-cyclobutane scaffold bearing a hydroxymethyl group and a bench-stable carbamate protecting group. This configuration enables selective functionalization at the alcohol site while maintaining stereochemical integrity during synthetic sequences. The molecule integrates seamlessly into complex molecular architectures requiring controlled reactivity and spatial orientation.

Application

tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate serves as a stable, bench-ready building block for cyclobutane-based scaffolds in medicinal chemistry. The trans-configured cyclobutane ring provides defined stereochemistry, while the hydroxymethyl group enables downstream functionalization via oxidation, protection, or coupling reactions. The Boc group ensures excellent stability and facilitates straightforward deprotection under mild acidic conditions. This compound functions reliably in multi-step syntheses requiring stereocontrolled cyclobutane incorporation.

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 58.56
LogP 1.282
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Fatty ring compounds Cyclobutane compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

167081-37-0 sigma167081-37-0 manufacturer167081-37-0 price167081-37-0 structure167081-37-0 SDSbuy 167081-37-0167081-37-0 supplier167081-37-0 uses167081-37-0 molecular weightprice of 167081-37-0167081-37-0 chemical name formula of 167081-37-0

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate

CAS No. 167081-37-0

Recommended Products