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CS-W001157 4
Total: USD 88.00

4-(tert-Butyl)cyclohexan-1-amine

  • CAS No. 5400-88-4

  • Cat. No. CS-0120029
  • Purity≥97%
  • MDL No.MFCD00013763

*For research and further manufacturing use only, not for direct human use.

4-(tert-Butyl)cyclohexan-1-amine|CS-0120029

Structure of 5400-88-4

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General Information

  • CAS No. 5400-88-4
  • Cat. No. CS-0120029
  • Purity ≥97%
  • MDL No. MFCD00013763
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₁N
  • Molecular Weight 155.28
  • Synonym(s) 4-tert-Butylcyclohexylamine (cis- and trans- mixture)
  • SMILES NC1CCC(C(C)(C)C)CC1

Description

4-(tert-Butyl)cyclohexan-1-amine features a sterically hindered tert-butyl group that enhances stability and modulates reactivity. This bench-stable amine integrates readily into chiral scaffolds, offering robust functionality in asymmetric synthesis and medicinal chemistry applications.

Synthesis

  • Route1

    References

    • US5571815 A1, ;
  • Route2
    • 4-(Tert-butyl)cyclohexan-1-one oxime|CS-0314768
      4701-98-8
    • ~68%
    • In-stock
      4-(tert-Butyl)cyclohexan-1-amine|CS-0120029
      5400-88-4

    References

    • Pau, Amedeo; Boatto, Gianpiero; Palomba, Michele; Asproni, Battistina; Cerri, Riccardo; Palagiano, Francesco; Filippelli, Walter; Falcone, Giuseppe; Motola, Giulia Farmaco, 1999 , vol. 54, # 8 p. 524 - 532
  • Route3
    • 4-(Tert-butyl)cyclohexane-1-carboxylic acid|CS-0453487
      5451-55-8
    • ~%
    • In-stock
      4-(tert-Butyl)cyclohexan-1-amine|CS-0120029
      5400-88-4

    References

    • European Journal of Organic Chemistry, , # 4 p. 679 - 682

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H314
Precautionary Statements : P210-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.55
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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