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Structure of 5371-70-0
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Dimethyl 4-chloropyridine-2,6-dicarboxylate features a pyridine core bearing chloro and ester functionalities at the 4-, 2-, and 6-positions, enabling efficient integration into heterocyclic syntheses. The electron-deficient pyridine ring facilitates nucleophilic substitution, while the bench-stable dimethyl ester groups support straightforward functionalization under standard conditions.
Dimethyl 4-chloropyridine-2,6-dicarboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient construction of pyridine-based scaffolds through nucleophilic substitution and coupling reactions. The 4-chloro group exhibits high reactivity toward amines, thiols, and organometallic reagents, while the flanking ester functionalities allow for selective transformations. Its bench-stable nature and compatibility with standard purification methods make it ideal for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: