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CS-W001157 4
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3-(4-Oxo-3,4-dihydro-quinazolin-2-yl)-propionic acid

  • CAS No. 5368-37-6

  • Cat. No. CS-0213162
  • Purity≥98%
  • MDL No.MFCD03955531

*For research and further manufacturing use only, not for direct human use.

3-(4-Oxo-3,4-dihydro-quinazolin-2-yl)-propionic acid|CS-0213162

Structure of 5368-37-6

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General Information

  • CAS No. 5368-37-6
  • Cat. No. CS-0213162
  • Purity ≥98%
  • MDL No. MFCD03955531
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₀N₂O₃
  • Molecular Weight 218.21
  • Synonym(s) 3,4-Dihydro-4-oxo-
  • SMILES C1=CC=C2C(=C1)C(=NC(=N2)CCC(=O)O)O

Synthesis

  • Route1
    • In-stock
      Succinic anhydride|CS-0011581
      108-30-5
    • null|null
      28144-70-9
    • ~82%
    • In-stock
      3-(4-Oxo-3,4-dihydro-quinazolin-2-yl)-propionic acid|CS-0213162
      5368-37-6

    References

    • Usifoh Scientia Pharmaceutica, 2000 , vol. 68, # 3 p. 275 - 279
  • Route2
    • 4-((2-Carbamoylphenyl)amino)-4-oxobutanoic acid|CS-0306426
      306325-56-4
    • ~91%
    • In-stock
      3-(4-Oxo-3,4-dihydro-quinazolin-2-yl)-propionic acid|CS-0213162
      5368-37-6

    References

    • AMGEN INC.; BREGMAN, Howard; BUCHANAN, John L.; CHAKKA, Nagasree; DIMAURO, Erin F.; GUNAYDIN, Hakan; GUZMAN PEREZ, Angel; HUA, Zihao; HUANG, Xin Patent: WO2014/36022 A1, 2014 ; Location in patent: Paragraph 0209-0210 ;
  • Route3
    • null|null
      84312-74-3
    • ~72%
    • In-stock
      3-(4-Oxo-3,4-dihydro-quinazolin-2-yl)-propionic acid|CS-0213162
      5368-37-6

    References

    • Essawy, A.; El-Hashash, M. A.; El-Gendy, A. M.; Hamad, M. M. M. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 6 p. 593 - 595

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   83.31
  • LogP   1.3526
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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