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CS-W001157 4
Total: USD 88.00

(6-(Dimethylamino)-4-methylpyridin-3-yl)boronic acid

  • CAS No. 535934-70-4

  • Cat. No. CS-0175835
  • Purity≥95%
  • MDL No.MFCD12912694

*For research and further manufacturing use only, not for direct human use.

(6-(Dimethylamino)-4-methylpyridin-3-yl)boronic acid|CS-0175835

Structure of 535934-70-4

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General Information

  • CAS No. 535934-70-4
  • Cat. No. CS-0175835
  • Purity ≥95%
  • MDL No. MFCD12912694
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₃BN₂O₂
  • Molecular Weight 180.02
  • Synonym(s) 6-dimethylamino-4-methyl-pyridineboronic acid
  • SMILES CC1=CC(N(C)C)=NC=C1B(O)O

Description

This boronate moiety integrates a dimethylamino-substituted pyridine core, offering enhanced solubility and stability under standard conditions. The para-methyl group provides steric modulation, while the electron-rich heterocycle facilitates efficient cross-coupling reactions in palladium-catalyzed transformations.

Application

(6-(Dimethylamino)-4-methylpyridin-3-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. Its pyridine core provides excellent functional group tolerance and bench stability, while the boronic acid moiety facilitates reliable coupling with aryl and heteroaryl halides. The dimethylamino and methyl substituents enhance electron density at the reaction center, promoting reactivity in cross-coupling workflows common to medicinal chemistry and materials synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   56.59
  • LogP   -0.86418
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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