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CS-W001157 4
Total: USD 88.00

(5-Amino-2-fluoro-phenyl)-carbamic acid tert-butyl ester

  • CAS No. 535170-18-4

  • Cat. No. CS-0342317
  • Molecule weight226.25
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(5-Amino-2-fluoro-phenyl)-carbamic acid tert-butyl ester|CS-0342317

Structure of 535170-18-4

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General Information

  • CAS No. 535170-18-4
  • Cat. No. CS-0342317
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₅FN₂O₂
  • Molecular Weight 226.25
  • Synonym(s) tert-Butyl (5-amino-2-fluorophenyl)carbamate
  • SMILES CC(C)(OC(NC1=C(F)C=CC(N)=C1)=O)C

Synthesis

  • Route1
    • tert-Butyl (2-fluoro-5-nitrophenyl)carbamate|CS-0371753
      535170-15-1
    • ~87%
    • In-stock
      (5-Amino-2-fluoro-phenyl)-carbamic acid tert-butyl ester|CS-0342317
      535170-18-4

    References

    • Kuramoto, Yasuhiro; Ohshita, Yoshihiro; Yoshida, Jiro; Yazaki, Akira; Shiro, Motoo; Koike, Tohru Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1905 - 1917
  • Route2

    References

    • Hirose, Masaaki; Okaniwa, Masanori; Miyazaki, Tohru; Imada, Takashi; Ohashi, Tomohiro; Tanaka, Yuta; Arita, Takeo; Yabuki, Masato; Kawamoto, Tomohiro; Tsutsumi, Shunichirou; Sumita, Akihiko; Takagi, Terufumi; Sang, Bi-Ching; Yano, Jason; Aertgeerts, Kathleen; Yoshida, Sei; Ishikawa, Tomoyasu Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 18 p. 5600 - 5615
  • Route3

    References

    • Hirose, Masaaki; Okaniwa, Masanori; Miyazaki, Tohru; Imada, Takashi; Ohashi, Tomohiro; Tanaka, Yuta; Arita, Takeo; Yabuki, Masato; Kawamoto, Tomohiro; Tsutsumi, Shunichirou; Sumita, Akihiko; Takagi, Terufumi; Sang, Bi-Ching; Yano, Jason; Aertgeerts, Kathleen; Yoshida, Sei; Ishikawa, Tomoyasu Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 18 p. 5600 - 5615

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   2.7549
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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