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Structure of 53502-60-6
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1-(2-Chloroethyl)piperazine dihydrochloride is a reactive bifunctional building block featuring a chloroethyl group that readily undergoes nucleophilic substitution. This enables efficient conjugation to thiols or other nucleophiles, making it valuable for covalent labeling applications in chemical biology and drug discovery workflows.
1-(2-Chloroethyl)piperazine dihydrochloride serves as a versatile bifunctional electrophile in synthetic organic chemistry, enabling efficient alkylation of nucleophiles under mild conditions. The primary amine functionality facilitates conjugation with carboxylic acids and coupling to polymer supports, while the terminal chloroethyl group provides high reactivity toward amines, thiols, and other soft nucleophiles. Its crystalline solid form offers excellent bench stability and ease of handling, making it ideal for building blocks in medicinal chemistry and combinatorial library synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: