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CS-W001157 4
Total: USD 88.00

6-Chloropyridin-3-amine

  • CAS No. 5350-93-6

  • Cat. No. CS-W007481
  • Purity≥98%
  • MDL No.MFCD00006243

*For research and further manufacturing use only, not for direct human use.

6-Chloropyridin-3-amine|CS-W007481

Structure of 5350-93-6

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General Information

  • CAS No. 5350-93-6
  • Cat. No. CS-W007481
  • Purity ≥98%
  • MDL No. MFCD00006243
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅ClN₂
  • Molecular Weight 128.56
  • Synonym(s) None
  • SMILES ClC1=NC=C(N)C=C1

Description

5-Amino-2-chloropyridine undergoes Suzuki-Miyaura coupling with sterically hindered 2,6-dimethylphenylboronic acid. It undergoes facile temperature dependent displacement of chloride by bromide via Sandmeyer reaction to yield 2,5-dibromopyridine.5-Amino-2-chloropyridine was used in the synthesis of [2H5]2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine. It was used in identification and evaluation of molecularly imprinted polymers for the selective removal of potentially genotoxic aminopyridine impurities from pharmaceuticals.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.3172
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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