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CS-W001157 4
Total: USD 88.00

(Diphenylmethylene)hydrazine

  • CAS No. 5350-57-2

  • Cat. No. CS-W010590
  • Purity≥98%
  • MDL No.MFCD00007624
  • AREC Toxic Substance

*For research and further manufacturing use only, not for direct human use.

(Diphenylmethylene)hydrazine|CS-W010590

Structure of 5350-57-2

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General Information

  • CAS No. 5350-57-2
  • Cat. No. CS-W010590
  • Purity ≥98%
  • MDL No. MFCD00007624
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₂N₂
  • Molecular Weight 196.25
  • Synonym(s) hydrazine of benzophenone
  • SMILES N/N=C(C1=CC=CC=C1)/C2=CC=CC=C2

Description

Diphenylmethylene hydrazine serves as a key intermediate in heterocyclic synthesis, featuring a stable hydrazone linkage flanked by two aryl groups. This structure enables efficient coupling reactions and facilitates the construction of complex nitrogen-containing scaffolds under mild conditions.

Application

(Diphenylmethylene)hydrazine serves as a reliable building block for the synthesis of diverse heterocyclic scaffolds, particularly pyrazoles and triazoles, via cycloaddition and condensation reactions. Its robust bench stability and compatibility with common functional groups enable straightforward incorporation into complex molecular architectures. The molecule facilitates efficient access to pharmaceutically relevant frameworks through well-established reaction pathways.

Synthesis

  • Route1

    References

    • Yu, Jindi; Lian, Gaoyan; Zhang, Danwei Synthetic Communications, 2007 , vol. 37, # 1 p. 37 - 46
  • Route2

    References

    • Pasha; Nanjundaswamy Synthetic Communications, 2004 , vol. 34, # 21 p. 3827 - 3831
  • Route3
    • null|null
      908093-98-1
    • ~84%
    • In-stock
      (Diphenylmethylene)hydrazine|CS-W010590
      5350-57-2

    References

    • Cheng, Spencer; Hawley, M. Dale Journal of Organic Chemistry, 1986 , vol. 51, # 20 p. 3799 - 3804

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS09
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H317-H411
Precautionary Statements : P280-P302+P352

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Computational Chemistry Data

  • TPSA   38.38
  • LogP   2.3977
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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