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Structure of 53388-86-6
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This 5-bromo-3,3-dimethyl-2,3-dihydro-1H-indole features a brominated indole core with a sterically shielded dimethyl substitution at the 3-position, enhancing stability and directing electrophilic reactions selectively. The saturated C2–C3 bond enables controlled reactivity in transition metal-catalyzed couplings. This scaffold integrates readily into bioactive molecules requiring halogenated aromatic motifs.
5-Bromo-3,3-dimethyl-2,3-dihydro-1H-indole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo substituent. The 3,3-dimethyl substitution enhances steric protection and bench stability, while the dihydroindole core facilitates integration into heterocyclic scaffolds. Its functional group tolerance supports efficient derivatization in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: