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CS-W001157 4
Total: USD 88.00

6-Bromoquinoline

  • CAS No. 5332-25-2

  • Cat. No. CS-W007403
  • Purity≥97%
  • MDL No.MFCD00024023

*For research and further manufacturing use only, not for direct human use.

6-Bromoquinoline|CS-W007403

Structure of 5332-25-2

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General Information

  • CAS No. 5332-25-2
  • Cat. No. CS-W007403
  • Purity ≥97%
  • MDL No. MFCD00024023
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆BrN
  • Molecular Weight 208.06
  • Synonym(s) 6-Br-Quinoline
  • SMILES C1=CC=C2C(=N1)C=CC(=C2)Br

Description

6-Bromoquinoline is a halogenated heterocycle featuring a bromine atom at the 6-position of the quinoline core. This electron-deficient scaffold integrates readily into cross-coupling reactions, serving as a key building block in pharmaceutical synthesis and materials science. The para-brominated configuration enhances reactivity in palladium-catalyzed transformations while maintaining stability under standard handling conditions.

Application

6-Bromoquinoline serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. Its bromine substituent offers high reactivity under standard conditions while maintaining bench stability, facilitating efficient construction of biaryl and heteroaryl architectures. The quinoline core provides inherent π-conjugation and metal-chelating properties, making it valuable for synthesizing fluorescent probes, kinase inhibitors, and organic semiconductors.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.9973
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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