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CS-W001157 4
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trans-4-(Boc-Amino)cyclohexanecarboxylic acid

  • CAS No. 53292-89-0

  • Cat. No. CS-W004224
  • Purity≥97%
  • MDL No.MFCD01862293

*For research and further manufacturing use only, not for direct human use.

trans-4-(Boc-Amino)cyclohexanecarboxylic acid|CS-W004224

Structure of 53292-89-0

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General Information

  • CAS No. 53292-89-0
  • Cat. No. CS-W004224
  • Purity ≥97%
  • MDL No. MFCD01862293
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₄
  • Molecular Weight 243.30
  • Synonym(s) trans-4-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic acid
  • SMILES O=C(OC(C)(C)C)N[C@@H]1CC[C@H](CC1)C(=O)O

Description

trans-4-(Boc-Amino)cyclohexanecarboxylic acid features a rigid, conformationally stable cyclohexane scaffold with a Boc-protected amino group positioned trans to the carboxylic acid. This stereochemical configuration enhances solubility and stability during peptide coupling workflows. The protected amine facilitates direct incorporation into peptidic sequences without side-reaction interference.

Application

trans-4-(Boc-Amino)cyclohexanecarboxylic acid serves as a versatile chiral building block for the synthesis of bioactive molecules and heterocyclic scaffolds. The Boc-protected amine exhibits excellent bench stability and compatibility with standard coupling conditions, enabling straightforward incorporation into peptide-like architectures. Its rigid trans-cyclohexane framework provides defined stereochemistry and conformational restraint, facilitating predictable reactivity in functional group interconversions and ring-forming processes.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.1545
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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