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CS-W001157 4
Total: USD 88.00

3-Methoxy-N,N-dimethylpropanamide

  • CAS No. 53185-52-7

  • Cat. No. CS-0210107
  • Purity≥97%
  • MDL No.MFCD18970488

*For research and further manufacturing use only, not for direct human use.

3-Methoxy-N,N-dimethylpropanamide|CS-0210107

Structure of 53185-52-7

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General Information

  • CAS No. 53185-52-7
  • Cat. No. CS-0210107
  • Purity ≥97%
  • MDL No. MFCD18970488
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO₂
  • Molecular Weight 131.17
  • Synonym(s) Propanamide, 3-methoxy-N,N-dimethyl-
  • SMILES CN(C)C(=O)CCOC

Description

3-Methoxy-N,N-dimethylpropanamide features a polar amide group paired with a methoxy substituent, enabling enhanced solubility in organic solvents while maintaining stability under standard bench conditions. This combination supports efficient integration into synthetic pathways requiring moderate polarity and reliable handling.

Application

3-Methoxy-N,N-dimethylpropanamide serves as a versatile synthetic intermediate in medicinal chemistry, enabling efficient construction of bioactive heterocycles and peptide-like scaffolds. Its amide functionality offers enhanced stability and favorable solubility profiles, while the methoxy group provides a handle for selective derivatization. The N,N-dimethyl substitution enhances metabolic resistance and improves lipophilicity, making it well-suited for lead optimization campaigns. This compound functions reliably in standard coupling and functionalization protocols, facilitating streamlined synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319-H361-H373
Precautionary Statements : P260-P264-P280-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   0.1111
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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