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CS-W001157 4
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1-Hydroxypyrene

  • CAS No. 5315-79-7

  • Cat. No. CS-W014791
  • Purity≥98%
  • MDL No.MFCD00044543

*For research and further manufacturing use only, not for direct human use.

1-Hydroxypyrene|CS-W014791

Structure of 5315-79-7

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General Information

  • CAS No. 5315-79-7
  • Cat. No. CS-W014791
  • Purity ≥98%
  • MDL No. MFCD00044543
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₀O
  • Molecular Weight 218.25
  • Synonym(s) None
  • SMILES OC1=C(C2=C34)C=CC4=CC=CC3=CC=C2C=C1

Description

1-Hydroxypyrene features a phenolic hydroxyl group appended to the pyrene scaffold, enhancing solubility and enabling direct conjugation in fluorescent labeling applications. This derivative serves as a robust probe for bioconjugation, leveraging its photostable, high-quantum-yield emission under UV excitation.

Application

1-Hydroxypyrene serves as a stable, bench-ready building block for polycyclic aromatic compound synthesis. Its hydroxyl group enables straightforward derivatization via esterification, etherification, or transition-metal-catalyzed coupling reactions. The rigid pyrenyl core provides excellent thermal stability and fluorescence properties, making it valuable in materials chemistry and as a structural motif in advanced organic frameworks.

Synthesis

  • Route1

    References

    • Huang, Ling; Cui, Xiaoneng; Therrien, Bruno; Zhao, Jianzhang Chemistry - A European Journal, 2013 , vol. 19, # 51 p. 17472 - 17482
  • Route2

    References

    • Babu; Sangeetha; Vijaykumar; Maitra, Uday; Rissanen, Kari; Raju Chemistry - A European Journal, 2003 , vol. 9, # 9 p. 1922 - 1932
  • Route3
    • Pyren-1-yl acetate|CS-0970600
      78751-40-3
    • ~76%
    • In-stock
      1-Hydroxypyrene|CS-W014791
      5315-79-7

    References

    • Harvey, Ronald G.; Hahn, Jung-Tai; Bukowska, Maria; Jackson, Henry Journal of Organic Chemistry, 1990 , vol. 55, # 25 p. 6161 - 6166

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   4.2896
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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