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CS-W001157 4
Total: USD 88.00

4'-Methoxy-[1,1'-biphenyl]-4-carbaldehyde

  • CAS No. 52988-34-8

  • Cat. No. CS-0071999
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4'-Methoxy-[1,1'-biphenyl]-4-carbaldehyde|CS-0071999

Structure of 52988-34-8

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General Information

  • CAS No. 52988-34-8
  • Cat. No. CS-0071999
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₂O₂
  • Molecular Weight 212.24
  • Synonym(s) 4-Methoxy-Biphenyl-4-Carboxaldehyde
  • SMILES O=CC1=CC=C(C=C1)C2=CC=C(OC)C=C2

Description

4'-Methoxy-[1,1'-biphenyl]-4-carbaldehyde features a para-methoxy-substituted biphenyl scaffold with a terminal aldehyde group, delivering enhanced solubility and stability under standard conditions. This electron-rich aryl aldehyde integrates readily into Suzuki-Miyaura coupling workflows and serves as a key intermediate in the synthesis of functionalized biaryl architectures for pharmaceutical and materials applications.

Application

4'-Methoxy-[1,1'-biphenyl]-4-carbaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling the synthesis of functionalized biaryl scaffolds. Its aldehyde functionality facilitates efficient coupling reactions, including reductive amination and Wittig transformations, while the methoxy group enhances solubility and modulates electronic properties. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   3.1747
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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