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CS-W001157 4
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6-Hydroxy-2-naphthonitrile

  • CAS No. 52927-22-7

  • Cat. No. CS-W002854
  • Molecule weight169.18
  • Purity≥97%
  • MDL No.MFCD01863480

*For research and further manufacturing use only, not for direct human use.

6-Hydroxy-2-naphthonitrile|CS-W002854

Structure of 52927-22-7

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General Information

  • CAS No. 52927-22-7
  • Cat. No. CS-W002854
  • Purity ≥97%
  • MDL No. MFCD01863480
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₇NO
  • Molecular Weight 169.18
  • Synonym(s) 6-Cyano-2-naphthol
  • SMILES N#Cc1ccc2c(c1)ccc(c2)O

Description

6-Cyano-2-naphthol (6CN2) is an aromatic alcohol that can be synthesized from 6-bromo-2-naphthol. It is a superphotoacid with the ground state pKa* value of 8.4 and excited state pKavalue of 0.2, respectively. 6CN2 protonates PANI-ES (polyaniline emeraldine salt) to form PANI-EB (emeraldine base), which shows enhanced conductivity. The proton-transfer kinetics and photophysical behavior of 6CN2 have been investigated.6-Cyano-2-naphthol (6-Hydroxy-2-naphthonitrile, 2-cyano-6-naphthol) may be used in the preparation of:5-bromo-6-hydroxy-2-naphthonitrile5,7-dibromo-6-hydroxy-2-naphthonitrile5-chloro-6-hydroxy-2-naphthonitrile6-(2-imidazolyl)-2-naphtholdodecaethylene glycol di-6-cyano-2-naphthyl ether6-cyano-2-naphthyl trifluoremethanesufonate2-(6-cyano-naphthyl)2,3,4-tri-O-acetyl--D-xylopyranoside1,5-bis(7-amidino-2-naphthalenoxy)-3-oxapentane dihydrochloride

Synthesis

  • Route1
    • Naproxen impurity 6|CS-0259671
      67886-70-8
    • ~93%
    • In-stock
      6-Hydroxy-2-naphthonitrile|CS-W002854
      52927-22-7

    References

    • LABORATORIOS MENARINI S.A. Patent: EP775133 B1, 2001 ;
  • Route2

    References

    • Aoyama; Okutome; NakayamaT.; Yaegashi; Matsui; Nunomura; Kurumi; Sakurai; Fujii Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 4 p. 1458 - 1471
  • Route3
    • null|null
      3845-63-4
    • ~%
    • In-stock
      6-Hydroxy-2-naphthonitrile|CS-W002854
      52927-22-7

    References

    • Journal of Organic Chemistry USSR (English Translation), , vol. 17, # 2 p. 303 - 306 Zhurnal Organicheskoi Khimii, , vol. 17, # 2 p. 358 - 361

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   44.02
  • LogP   2.41708
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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