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CS-W001157 4
Total: USD 88.00

(R,R)-Phenyl-BPE

  • CAS No. 528565-79-9

  • Cat. No. CS-0086378
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R,R)-Phenyl-BPE|CS-0086378

Structure of 528565-79-9

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General Information

  • CAS No. 528565-79-9
  • Cat. No. CS-0086378
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₄H₃₆P₂
  • Molecular Weight 506.60
  • Synonym(s) 1,2-Bis((2R,5R)-2,5-diphenylphospholan-1-yl)ethane
  • SMILES [C@H]1(C2=CC=CC=C2)CC[C@H](C3=CC=CC=C3)P1CCP4[C@@H](C5=CC=CC=C5)CC[C@@H]4C6=CC=CC=C6

Application

(R,R)-Phenyl-BPE serves as a highly effective chiral ligand in asymmetric transition metal catalysis, enabling enantioselective transformations such as hydrogenation and allylic alkylation. Its robust bench stability, excellent functional group tolerance, and well-documented stereocontrol make it a practical choice for synthetic chemists developing chiral intermediates in medicinal chemistry and process scale-up.

Synthesis

  • Route1
    • (2R,5R)-1-Hydroxy-2,5-diphenylphospholane 1-oxide|CS-0162435
      226393-33-5
    • ~%
    • In-stock
      (R,R)-Phenyl-BPE|CS-0086378
      528565-79-9

    References

    • Pilkington, Christopher J.; Zanotti-Gerosa, Antonio Organic Letters, 2003 , vol. 5, # 8 p. 1273 - 1275

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   10.503
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   7

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