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CS-W001157 4
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3,4-Dihydro-2H-pyrano[2,3-c]pyridine-6-carbaldehyde

  • CAS No. 527681-61-4

  • Cat. No. CS-0022199
  • Purity≥98%
  • MDL No.MFCD18802894

*For research and further manufacturing use only, not for direct human use.

3,4-Dihydro-2H-pyrano[2,3-c]pyridine-6-carbaldehyde|CS-0022199

Structure of 527681-61-4

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General Information

  • CAS No. 527681-61-4
  • Cat. No. CS-0022199
  • Purity ≥98%
  • MDL No. MFCD18802894
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉NO₂
  • Molecular Weight 163.17
  • Synonym(s) 3,4-dihydro-2H-Pyrano[2,3-c]pyridine-6-carboxaldehyde
  • SMILES O=CC1=CC(CCCO2)=C2C=N1

Description

This pyrano[2,3-c]pyridine aldehyde features a fused tricyclic scaffold with a reactive aldehyde group at the C6 position, enabling direct coupling in multicomponent reactions. The electron-rich heterocyclic framework enhances stability under standard conditions while facilitating selective functionalization.

Application

3,4-Dihydro-2H-pyrano[2,3-c]pyridine-6-carbaldehyde serves as a versatile heterocyclic building block for the synthesis of pharmacologically relevant scaffolds. Its aldehyde functionality enables efficient derivatization via reductive amination, Wittig reactions, and nucleophilic addition, while the fused pyranopyridine core offers structural rigidity and favorable physicochemical properties. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic campaigns in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   1.2191
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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