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CS-W001157 4
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2-Bromo-1-(2-furyl)ethanone

  • CAS No. 15109-94-1

  • Cat. No. CS-0310036
  • Purity≥97%
  • MDL No.MFCD04038962

*For research and further manufacturing use only, not for direct human use.

2-Bromo-1-(2-furyl)ethanone|CS-0310036

Structure of 15109-94-1

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General Information

  • CAS No. 15109-94-1
  • Cat. No. CS-0310036
  • Purity ≥97%
  • MDL No. MFCD04038962
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrO₂
  • Molecular Weight 189.01
  • Synonym(s) BUTTPARK 147\06-34
  • SMILES BrCC(=O)C1OC=CC=1

Description

2-Bromo-1-(2-furyl)ethanone features a reactive bromo ketone moiety integrated with a furan ring, enabling direct incorporation into cross-coupling and functionalization workflows. This bench-stable compound serves as a key intermediate for synthesizing heterocyclic architectures in medicinal chemistry and materials science.

Application

2-Bromo-1-(2-furyl)ethanone serves as a versatile building block in heterocyclic synthesis, enabling efficient access to furan-containing scaffolds via nucleophilic substitution and coupling reactions. Its bromo group facilitates Pd-catalyzed cross-coupling, while the ketone functionality supports enolization and condensation pathways. The molecule exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Synthesis

  • Route1

    References

    • Bennett, Grace A.; Mullen, George B.; Mitchell, Jeffrey T.; Jones, Wendy E.; Allen, Stanley D.; et al. European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 579 - 584
  • Route2
    • null|null
      62889-08-1
    • ~93%
    • In-stock
      2-Bromo-1-(2-furyl)ethanone|CS-0310036
      15109-94-1
    • null|null
      17357-25-4

    References

    • Synthetic Communications, , vol. 21, # 1 p. 11 - 16
  • Route3
    • In-stock
      2-Acetylfuran, ≥99%|CS-1269059
      1192-62-7
    • null|null
      60-29-7
    • ~%
    • In-stock
      2-Bromo-1-(2-furyl)ethanone|CS-0310036
      15109-94-1

    References

    • US5856511 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   30.21
  • LogP   1.8572
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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