Lot numbers can be found on the outside label of a product:
Aminodiphenylmethane hydrochloride
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CAS No. 5267-34-5
- Cat. No. CS-0022274
- Purity≥95%
- MDL No.MFCD00013023
*For research and further manufacturing use only, not for direct human use.
Structure of 5267-34-5
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General Information
- CAS No. 5267-34-5
- Cat. No. CS-0022274
- Purity ≥95%
- MDL No. MFCD00013023
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₃H₁₄ClN
- Molecular Weight 219.71
- Synonym(s) α-Aminodiphenylmethane Hydrochloride
- SMILES NC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
Description
Aminodiphenylmethane hydrochloride offers a stable, moisture-tolerant platform for constructing aromatic amine derivatives. This bench-stable salt features a diphenylmethyl scaffold bearing a primary amine group, enabling direct incorporation into pharmaceutical intermediates and functional materials. The hydrochloride form enhances solubility in polar solvents while simplifying handling and storage.
Application
Aminodiphenylmethane hydrochloride serves as a stable, bench-ready building block for the synthesis of aromatic amines and heterocyclic scaffolds. Its dual phenyl groups and primary amine functionality enable straightforward functionalization in standard coupling reactions, including reductive amination and electrophilic substitution. The salt form enhances solubility and handling, facilitating purification and integration into multi-step synthetic sequences common in medicinal chemistry and materials science applications.
Synthesis
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Route1
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In-stock
574-66-3 - ~%
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In-stock
5267-34-5
References
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INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES; Shi, Jiangong; Zhang, Jianjun; Yue, Zhenggang; Li, Min; Zhu, Chenggen; Zhang, Ying; Zi, Jiachen; Wang, Yafang; Fan, Xiaona; Xu, Ruiming; Lin, Sheng; Li, Yan; Yang, Yongchun; Sheng, Li Patent: US2013/45942 A1, 2013 ; Location in patent: Paragraph 0379 ;
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Route2
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In-stock
119-61-9 - ~%
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In-stock
5267-34-5
References
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Adembri, G.; Camparini, A.; Ponticelli, F.; Scotton, M. Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 2 p. 321 - 326
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Route3
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5350-59-4 - ~93%
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In-stock
5267-34-5
References
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Li, Minyan; Yuecel, Baris; Adrio, Javier; Bellomo, Ana; Walsh, Patrick J. Chemical Science, 2014 , vol. 5, # 6 p. 2383 - 2391
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 26.02
- LogP 3.1565
- H_Acceptors 1
- H_Donors 1
- Rotatable_Bonds 2
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