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Structure of 52571-45-6
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N4-Benzoyl-2’-O-methylcytidine features a benzoyl group at the cytosine N4 position and a 2’-O-methyl modification on the ribose, enhancing nuclease resistance and cellular uptake. This dual-functionalized nucleoside integrates readily into oligonucleotide synthesis for therapeutic applications requiring improved stability and binding affinity.
N4-Benzoyl-2’-O-methylcytidine serves as a key nucleoside building block for the synthesis of modified oligonucleotides, enabling site-specific incorporation of cytosine analogs with enhanced stability and resistance to enzymatic degradation. The 2’-O-methyl modification improves nuclease resistance, while the N4-benzoyl group provides orthogonal protection for subsequent deprotection strategies. This compound facilitates efficient solid-phase synthesis and is well-suited for applications in antisense therapeutics and RNA-based research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: