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CS-W001157 4
Total: USD 88.00

1-Iodo-2-(2-iodoethoxy)ethane

  • CAS No. 34270-90-1

  • Cat. No. CS-W011980
  • Purity≥98%
  • MDL No.MFCD00092250

*For research and further manufacturing use only, not for direct human use.

1-Iodo-2-(2-iodoethoxy)ethane|CS-W011980

Structure of 34270-90-1

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General Information

  • CAS No. 34270-90-1
  • Cat. No. CS-W011980
  • Purity ≥98%
  • MDL No. MFCD00092250
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈I₂O
  • Molecular Weight 325.92
  • Synonym(s) None
  • SMILES ICCOCCI

Description

1-Iodo-2-(2-iodoethoxy)ethane features a bis-iodinated ethoxy chain enabling efficient coupling in multi-functionalization workflows. This bifunctional iodide integrates readily into cross-coupling reactions, offering high reactivity and compatibility under standard conditions. The molecule's dual electrophilic sites facilitate sequential functionalization with minimal purification steps.

Application

1-Iodo-2-(2-iodoethoxy)ethane serves as a versatile diiodoalkylating agent, enabling efficient introduction of bifunctional alkyl chains in synthetic sequences. Its dual reactive iodide groups facilitate cross-coupling reactions and heterocycle construction, particularly in the synthesis of cyclic ethers and bioactive scaffolds. The molecule exhibits good bench stability and ease of purification, making it well-suited for iterative functionalization workflows in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • null|null
      111-44-4
    • ~97%
    • In-stock
      1-Iodo-2-(2-iodoethoxy)ethane|CS-W011980
      34270-90-1

    References

    • Bristol-Myers Squibb Company Patent: US2007/112190 A1, 2007 ; Location in patent: Page/Page column 28 ;
  • Route2

    References

    • Jensen, Marie; Schmidt, Steffen; Fedosova, Natalya U.; Mollenhauer, Jan; Jensen, Henrik H. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 7 p. 2407 - 2417

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05,GHS07
Signal Word : Danger
UN#: 2924
Class : 3,8
Packing Group : Ⅲ
Hazard Statements : H225-H317-H318
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   1.873
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   4

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