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CS-W001157 4
Total: USD 88.00

2-Chloro-4-hydrazinylpyrimidine

  • CAS No. 52476-87-6

  • Cat. No. CS-0113126
  • Molecule weight144.56
  • Purity≥98%
  • MDL No.MFCD06658201

*For research and further manufacturing use only, not for direct human use.

2-Chloro-4-hydrazinylpyrimidine|CS-0113126

Structure of 52476-87-6

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General Information

  • CAS No. 52476-87-6
  • Cat. No. CS-0113126
  • Purity ≥98%
  • MDL No. MFCD06658201
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅ClN₄
  • Molecular Weight 144.56
  • Synonym(s) pyrimidine, 2-chloro-4-hydrazinyl-
  • SMILES NNC1=NC(Cl)=NC=C1

Synthesis

  • Route1
    • null|null
      3934-20-1
    • ~82%
    • 2-Chloro-4-hydrazinylpyrimidine|CS-0113126
      52476-87-6

    References

    • Wang, Yi-Feng; Liu, Wei-Min; Zhu, You-Quan; Zou, Xiao-Mao; Hu, Fang-Zhong; Yang, Hua-Zheng Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 5 p. 1275 - 1280
  • Route2
    • null|null
      3934-20-1
    • null|null
      7727-37-9
    • ~22%
    • 2-Chloro-4-hydrazinylpyrimidine|CS-0113126
      52476-87-6

    References

    • VERTEX PHARMACEUTICALS INCORPORATED Patent: WO2004/46120 A2, 2004 ; Location in patent: Page 162 ; WO 2004/046120 A2
  • Route3
    • null|null
      3934-20-1
    • ~%
    • 4-Chloro-2-hydrazinylpyrimidine|CS-0687847
      1158984-54-3
    • 2-Chloro-4-hydrazinylpyrimidine|CS-0113126
      52476-87-6

    References

    • SMITHKLINE BEECHAM CORPORATION Patent: WO2009/68652 A1, 2009 ; Location in patent: Page/Page column 30 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.83
  • LogP   0.4156
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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