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CS-W001157 4
Total: USD 88.00

m-PEG5-SH

  • CAS No. 524030-00-0

  • Cat. No. CS-0116176
  • Purity≥95%
  • MDL No.MFCD16619320

*For research and further manufacturing use only, not for direct human use.

m-PEG5-SH|CS-0116176

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General Information

  • CAS No. 524030-00-0
  • Cat. No. CS-0116176
  • Purity ≥95%
  • MDL No. MFCD16619320
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₄O₅S
  • Molecular Weight 268.37
  • Synonym(s) None
  • SMILES COCCOCCOCCOCCOCCS

Description

m-PEG5-SH features a thiol terminus on a monomethoxy-polyethylene glycol chain of five ethylene oxide units, offering enhanced solubility and stability in aqueous environments. This conjugation-ready reagent enables site-specific bioconjugation through selective maleimide-thiol coupling, ideal for linker development in antibody-drug conjugates and peptide engineering.

Application

m-PEG5-SH serves as a versatile bifunctional building block for conjugation and polymer chemistry, offering a well-defined five-ether unit spacer between a terminal thiol group and a monofunctional end. The thiol functionality enables efficient maleimide-based bioconjugation or gold surface attachment, while the PEG backbone imparts excellent solubility, stability, and resistance to non-specific binding. Its predictable length and reliable reactivity make it ideal for constructing drug delivery systems, peptide-protein hybrids, and surface-functionalized nanomaterials.

Safety Information

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GHS Pictogram :
GHS No : GHS06,GHS09
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H332-H410
Precautionary Statements : P261-P264-P270-P271-P273-P304+P340-P330-P391-P405-P501

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Computational Chemistry Data

  • TPSA   46.15
  • LogP   0.629
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   14

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