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CS-W001157 4
Total: USD 88.00

2-(5-Ethylpyridin-2-yl)ethanol

  • CAS No. 5223-06-3

  • Cat. No. CS-W002400
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(5-Ethylpyridin-2-yl)ethanol|CS-W002400

Structure of 5223-06-3

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General Information

  • CAS No. 5223-06-3
  • Cat. No. CS-W002400
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO
  • Molecular Weight 151.21
  • Synonym(s) 5-ETHYL-2-PYRIDYLETHANOL
  • SMILES CCC1=CN=C(CCO)C=C1

Description

This ethylpyridine-functionalized ethanol integrates readily into synthetic workflows, offering a bench-stable, moisture-tolerant scaffold for constructing bioactive molecules and advanced materials.

Application

2-(5-Ethylpyridin-2-yl)ethanol serves as a versatile building block in medicinal chemistry, enabling the construction of pyridine-containing scaffolds via standard functional group transformations. Its ethylpyridine core provides favorable lipophilicity and metabolic stability, while the terminal hydroxyl group facilitates derivatization through etherification, esterification, or activation for coupling reactions. Bench-stable and readily purified by distillation or chromatography, it functions effectively in multi-step syntheses requiring orthogonal reactivity and compatibility with common protecting group strategies.

Synthesis

  • Route1
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      104-90-5
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      50-00-0
    • ~%
    • In-stock
      2-(5-Ethylpyridin-2-yl)ethanol|CS-W002400
      5223-06-3

    References

    • Chemische Berichte, , vol. 23, p. 2726
  • Route2
    • null|null
      104-90-5
    • ~%
    • In-stock
      2-(5-Ethylpyridin-2-yl)ethanol|CS-W002400
      5223-06-3

    References

    • US2009/118514 A1, ;
  • Route3
    • null|null
      104-90-5
    • null|null
      50-00-0
    • ~%
    • null|null
      5408-74-2
    • In-stock
      2-(5-Ethylpyridin-2-yl)ethanol|CS-W002400
      5223-06-3

    References

    • Journal of the American Chemical Society, , vol. 68, p. 1368 Org. Synth. Coll. Vol., , vol. IV, p. 451

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H312-H318-H335
Precautionary Statements : P261-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.1788
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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