Lot numbers can be found on the outside label of a product:
Pratraxa impurity 1
-
CAS No. 52059-53-7
- Cat. No. CS-W021390
- Purity≥98%
- MDL No.MFCD00045998
*For research and further manufacturing use only, not for direct human use.
Structure of 52059-53-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 52059-53-7
- Cat. No. CS-W021390
- Purity ≥98%
- MDL No. MFCD00045998
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₉FO
- Molecular Weight 140.16
- Synonym(s) None
- SMILES OCCC1=CC(F)=CC=C1
Description
2-(3-Fluorophenyl)ethanol is a bench-stable, moisture-tolerant arylalkanol featuring a fluorinated aromatic ring that imparts enhanced metabolic stability. This compound integrates readily into synthetic routes for pharmaceutical intermediates and bioactive molecules, where its polar hydroxyl group enables efficient derivatization. The para-fluoro substitution influences electronic properties favorably in coupling reactions.
Application
2-(3-Fluorophenyl)ethanol serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive compounds through standard functional group interconversions. Its bench-stable nature and compatibility with common transformations—such as oxidation to the aldehyde or carboxylic acid, and coupling reactions—facilitate efficient access to pharmaceutically relevant scaffolds. The ortho-fluoro substitution enhances metabolic stability and modulates electronic properties, making it a practical choice for lead optimization campaigns.
Synthesis
-
Route1
-
In-stock
331-25-9 - ~96%
-
In-stock
52059-53-7
References
-
Schmidt, Axel M.; Eilbracht, Peter Journal of Organic Chemistry, 2005 , vol. 70, # 14 p. 5528 - 5535
-
-
Route2
-
In-stock
64123-77-9 - ~%
-
In-stock
52059-53-7
References
-
GRUeNENTHAL GMBH; FRANK, Robert; BAHRENBERG, Gregor; CHRISTOPH, Thomas; SCHIENE, Klaus; DE VRY, Jean; DAMANN, Nils; FRORMANN, Sven; LESCH, Bernhard; LEE, Jeewoo; KIM, Yong-Soo; KIM, Myeong-Seop Patent: WO2010/127855 A1, 2010 ; Location in patent: Page/Page column 131; 132 ;
-
-
Route3
-
75-21-8 -
In-stock
1073-06-9 - ~77%
-
In-stock
52059-53-7
References
-
Marzi, Elena; Spitaleri, Andrea; Mongin, Florence; Schlosser, Manfred European Journal of Organic Chemistry, 2002 , # 15 p. 2508 - 2517
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 20.23
- LogP 1.3605
- H_Acceptors 1
- H_Donors 1
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Pratraxa impurity 1 sigmaPratraxa impurity 1 manufacturerPratraxa impurity 1 pricePratraxa impurity 1 structurePratraxa impurity 1 SDSbuy Pratraxa impurity 1Pratraxa impurity 1 supplierPratraxa impurity 1 usesPratraxa impurity 1 molecular weightprice of Pratraxa impurity 1Pratraxa impurity 1 chemical name formula of Pratraxa impurity 1