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CS-W001157 4
Total: USD 88.00

Pyrimidin-2-ol

  • CAS No. 51953-13-0

  • Cat. No. CS-0032184
  • Purity≥95%
  • MDL No.MFCD00047358

*For research and further manufacturing use only, not for direct human use.

Pyrimidin-2-ol|CS-0032184

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General Information

  • CAS No. 51953-13-0
  • Cat. No. CS-0032184
  • Purity ≥95%
  • MDL No. MFCD00047358
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄N₂O
  • Molecular Weight 96.09
  • Synonym(s) 2-Pyrimidinol (7CI,9CI)
  • SMILES OC1=NC=CC=N1

Description

Pyrimidin-2-ol delivers a reactive hydroxyl group at the 2-position of a heteroaromatic pyrimidine core, enabling direct incorporation into functionalized scaffolds. This bench-stable compound features enhanced solubility in polar solvents and serves as a key intermediate for medicinal chemistry campaigns targeting kinase inhibitors and nucleoside analogs.

Application

Pyrimidin-2-ol serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles through straightforward functionalization at the C2 position. Its stability under standard reaction conditions and compatibility with diverse coupling protocols facilitate rapid scaffold diversification. The molecule functions effectively as a key intermediate in the synthesis of nucleoside analogs and kinase inhibitors, offering reliable reactivity for both academic and industrial applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.01
  • LogP   0.1822
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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