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CS-W001157 4
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3-Aminotetrahydrothiophene 1,1-dioxide hydrochloride

  • CAS No. 51642-03-6

  • Cat. No. CS-W005500
  • Purity≥95%
  • MDL No.MFCD00456584

*For research and further manufacturing use only, not for direct human use.

3-Aminotetrahydrothiophene 1,1-dioxide hydrochloride|CS-W005500

Structure of 51642-03-6

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General Information

  • CAS No. 51642-03-6
  • Cat. No. CS-W005500
  • Purity ≥95%
  • MDL No. MFCD00456584
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClNO₂S
  • Molecular Weight 171.65
  • Synonym(s) TETRAHYDROTHIOPHEN-3-AMINIUM 1,1-DIOXIDE CHLORIDE
  • SMILES NC(C1)CCS1(=O)=O.Cl

Description

3-Aminotetrahydrothiophene 1,1-dioxide hydrochloride delivers a bench-stable, moisture-tolerant sulfonamide precursor featuring a primary amine within a saturated heterocyclic framework. This nitrogen-rich scaffold integrates readily into medicinal chemistry campaigns, offering enhanced solubility and metabolic stability in bioactive molecule design.

Application

3-Aminotetrahydrothiophene 1,1-dioxide hydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to sulfonamide-containing scaffolds. Its amine functionality facilitates straightforward derivatization via amidation, alkylation, and coupling reactions, while the sulfone group enhances metabolic stability and modulates solubility. The hydrochloride salt ensures excellent bench stability and ease of handling, supporting scalable synthesis and purification workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   60.16
  • LogP   -0.446
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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