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Structure of 5154-01-8
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5-Hydroxypyridin-2(1H)-one delivers a potent chelating scaffold with enhanced solubility and stability under physiological conditions. This heterocyclic ligand features a phenolic hydroxyl group adjacent to a nitrogen-rich pyridine core, enabling strong coordination to transition metals. The compound exhibits excellent bench stability and moisture tolerance, making it ideal for use in metal-binding applications and bioconjugation workflows.
5-Hydroxypyridin-2(1H)-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds through straightforward functionalization at the C5 hydroxyl and N1 positions. Its inherent stability under standard reaction conditions facilitates coupling reactions, derivatization, and incorporation into complex molecules. The compound exhibits favorable solubility and purification characteristics, making it well-suited for high-throughput synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: