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Methyl methyl-L-valinate hydrochloride

  • CAS No. 3339-44-4

  • Cat. No. CS-0137982
  • Purity≥97%
  • MDL No.MFCD00238325

*For research and further manufacturing use only, not for direct human use.

Methyl methyl-L-valinate hydrochloride|CS-0137982

Structure of 3339-44-4

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General Information

  • CAS No. 3339-44-4
  • Cat. No. CS-0137982
  • Purity ≥97%
  • MDL No. MFCD00238325
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₆ClNO₂
  • Molecular Weight 181.66
  • Synonym(s) N-Me-Val-Ome Hcl
  • SMILES CC(C)[C@@H](C(OC)=O)NC.[H]Cl

Description

Methyl methyl-L-valinate hydrochloride is a bench-stable, moisture-tolerant amino acid derivative featuring a protected L-valine side chain. This esterified form delivers enhanced solubility in organic solvents and simplifies handling during peptide synthesis workflows. The hydrochloride salt ensures high purity and facilitates efficient coupling reactions.

Application

Methyl methyl-L-valinate hydrochloride serves as a stable, bench-ready building block for peptide synthesis and medicinal chemistry applications. Its protected α-amino functionality enables straightforward coupling reactions with minimal epimerization, while the ester group facilitates selective transformations. The hydrochloride salt enhances solubility and handling, supporting efficient incorporation into complex molecular architectures.

Synthesis

  • Route1

    References

    • Chemistry - A European Journal, , vol. 17, # 3 p. 958 - 968
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    • In-stock
      Methyl methyl-L-valinate hydrochloride|CS-0137982
      3339-44-4

    References

    • Journal of Organic Chemistry, , vol. 59, # 9 p. 2437 - 2446
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 59, # 9 p. 2437 - 2446

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   0.8252
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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