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CS-W001157 4
Total: USD 88.00

(2,4-Difluorophenyl)hydrazine hydrochloride

  • CAS No. 51523-79-6

  • Cat. No. CS-W016004
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2,4-Difluorophenyl)hydrazine hydrochloride|CS-W016004

Structure of 51523-79-6

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General Information

  • CAS No. 51523-79-6
  • Cat. No. CS-W016004
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇ClF₂N₂
  • Molecular Weight 180.58
  • Synonym(s) 2,4-Difluorophenylhydrazine HCL
  • SMILES FC1=CC(F)=C(NN)C=C1.Cl

Description

(2,4-Difluorophenyl)hydrazine hydrochloride features a difluorinated aromatic ring that enhances electron deficiency and metabolic stability. This bench-stable hydrazine derivative integrates efficiently into heterocyclic scaffolds via condensation reactions, enabling rapid access to fluorinated azo dyes, triazoles, and bioactive intermediates under mild conditions.

Application

(2,4-Difluorophenyl)hydrazine hydrochloride serves as a valuable building block for the synthesis of heterocyclic scaffolds, particularly in the construction of pyrazoles and triazoles via cycloaddition reactions. Its fluorinated aryl moiety enhances metabolic stability and modulates electronic properties, while the hydrazine functionality enables reliable coupling with carbonyl compounds under mild conditions. The hydrochloride salt ensures improved bench stability and ease of handling, facilitating purification and scalability in medicinal chemistry campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   1.6722
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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