(4-Amino-2-chlorophenyl)methanol

Name: (4-Amino-2-chlorophenyl)methanol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 51420-25-8
Cat. No. CS-0199437
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(4-Amino-2-chlorophenyl)methanol|CS-0199437

Structure of 51420-25-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 51420-25-8
Cat. No. CS-0199437
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₈ClNO
Molecular Weight 157.60
Synonym(s) 4-amino-2-chloro-benzyl alcohol
SMILES C1=CC(=CC(=C1CO)Cl)N

Description

This bench-stable arylmethanol features a para-amino group flanked by a chloro substituent, enabling direct incorporation into pharmaceutical intermediates and functionalized biaryl scaffolds. The hydroxymethyl functionality supports derivatization under mild conditions, while the electron-donating amino moiety enhances reactivity in coupling processes.

Application

(4-Amino-2-chlorophenyl)methanol serves as a versatile building block in medicinal chemistry, enabling the synthesis of diverse heterocyclic scaffolds and functionalized aryl derivatives. Its dual amino and hydroxymethyl functionalities offer orthogonal reactivity for selective derivatization, while the chloro group facilitates palladium-catalyzed coupling reactions. The compound exhibits good bench stability and is amenable to standard purification techniques, making it well-suited for iterative synthesis workflows in API development.

Synthesis

Route1
- In-stock
  
  2457-76-3
- ~54%
- In-stock
  
  51420-25-8
References
- SGX Pharmaceuticals, Inc. Patent: US2007/173488 A1, 2007 ; Location in patent: Page/Page column 52 ;
Route2
- In-stock
  
  52301-88-9
- ~%
- In-stock
  
  51420-25-8
References
- Witt Chemische Berichte, 1892 , vol. 25, p. 83

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 46.25
LogP 1.4145
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

(4-Amino-2-chlorophenyl)methanol sigma(4-Amino-2-chlorophenyl)methanol manufacturer(4-Amino-2-chlorophenyl)methanol price(4-Amino-2-chlorophenyl)methanol structure(4-Amino-2-chlorophenyl)methanol SDSbuy (4-Amino-2-chlorophenyl)methanol(4-Amino-2-chlorophenyl)methanol supplier(4-Amino-2-chlorophenyl)methanol uses(4-Amino-2-chlorophenyl)methanol molecular weightprice of (4-Amino-2-chlorophenyl)methanol(4-Amino-2-chlorophenyl)methanol chemical name formula of (4-Amino-2-chlorophenyl)methanol

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(4-Amino-2-chlorophenyl)methanol

CAS No. 51420-25-8

Recommended Products