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CS-W001157 4
Total: USD 88.00

1-Methyladenine

  • CAS No. 5142-22-3

  • Cat. No. CS-0059558
  • Purity≥98%
  • MDL No.MFCD00010532

*For research and further manufacturing use only, not for direct human use.

1-Methyladenine|CS-0059558

Structure of 5142-22-3

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General Information

  • CAS No. 5142-22-3
  • Cat. No. CS-0059558
  • Purity ≥98%
  • MDL No. MFCD00010532
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇N₅
  • Molecular Weight 149.15
  • Synonym(s) None
  • SMILES NC1=C2N=CN=C2N=CN1C

Description

1-Methyladenine is a purine derivative featuring a methyl group at the 1-position, enhancing its stability and altering its hydrogen-bonding profile. This modification improves solubility in organic solvents while preserving the core nucleobase structure, making it valuable for synthetic studies in medicinal chemistry and oligonucleotide analog development.

Application

1-Methyladenine serves as a versatile purine scaffold for medicinal chemistry and nucleoside analog synthesis, offering a stable, bench-ready platform for site-specific derivatization at the N1 position. Its well-defined reactivity facilitates efficient functionalization in standard coupling protocols and supports orthogonal protection strategies in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   69.62
  • LogP   -0.1029
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   0

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