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CS-W001157 4
Total: USD 88.00

7-Methyl-1H-indazol-5-amine

  • CAS No. 844882-18-4

  • Cat. No. CS-0037313
  • Purity≥95%
  • MDL No.MFCD03792678

*For research and further manufacturing use only, not for direct human use.

7-Methyl-1H-indazol-5-amine|CS-0037313

Structure of 844882-18-4

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General Information

  • CAS No. 844882-18-4
  • Cat. No. CS-0037313
  • Purity ≥95%
  • MDL No. MFCD03792678
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉N₃
  • Molecular Weight None
  • Synonym(s) 7-methyl-1H-indazole-5-ylamine
  • SMILES CC1=C2C(=CC(=C1)N)C=NN2

Description

7-Methyl-1H-indazol-5-amine features a methyl-substituted indazole core with a primary amine at the 5-position, enabling direct functionalization in medicinal chemistry. The electron-rich heterocycle enhances binding affinity in kinase inhibitors and offers improved solubility over unsubstituted analogs. This bench-stable scaffold integrates readily into diverse molecular architectures.

Application

7-Methyl-1H-indazol-5-amine serves as a versatile scaffold for medicinal chemistry and materials science, enabling efficient construction of bioactive heterocycles. Its readily accessible amine functionality facilitates direct derivatization via amidation, alkylation, or electrophilic substitution. The molecule exhibits robust bench stability and compatibility with standard purification methods, making it well-suited for high-throughput synthesis and scale-up applications.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   54.7
  • LogP   1.45352
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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