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Structure of 51388-00-2
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2-(Azepan-1-yl)ethan-1-amine is a versatile amine building block featuring a seven-membered azepane ring linked to an ethylamine tether. This structure imparts enhanced solubility and tunable basicity, enabling efficient incorporation into bioactive molecules. The flexible alkyl chain facilitates conjugation in medicinal chemistry applications.
2-(Azepan-1-yl)ethan-1-amine serves as a versatile bifunctional building block in medicinal chemistry, combining a secondary amine and a flexible alkyl chain for conjugate addition and amide coupling reactions. Its azepane ring provides moderate basicity and enhanced metabolic stability compared to smaller heterocycles, while the ethylene linker enables efficient incorporation into diverse scaffolds. Bench-stable and readily purified by standard chromatography, it functions effectively in the synthesis of kinase inhibitors and CNS-targeted compounds.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: