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CS-W001157 4
Total: USD 88.00

5-Fluoro-1H-imidazole

  • CAS No. 30086-17-0

  • Cat. No. CS-0035781
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Fluoro-1H-imidazole|CS-0035781

Structure of 30086-17-0

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General Information

  • CAS No. 30086-17-0
  • Cat. No. CS-0035781
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₃FN₂
  • Molecular Weight 86.07
  • Synonym(s) 4-Fluoro-1H-imidazole
  • SMILES FC1=CN=CN1

Description

5-Fluoro-1H-imidazole is a bench-stable, electron-deficient heterocycle featuring a fluorine substituent at the 5-position. This configuration enhances its reactivity in transition metal-catalyzed couplings and functionalization processes. The molecule integrates readily into bioactive scaffolds due to its metabolic stability and polarity profile.

Synthesis

  • Route1

    References

    • US2010/144760 A1, ; Page/Page column 47; 48 ; US 20100144760 A1
  • Route2
    • 5-Nitroimidazole Metronidazole  Impurity|CS-0229038
      3034-38-6
    • ~30%
    • In-stock
      5-Fluoro-1H-imidazole|CS-0035781
      30086-17-0

    References

    • Chandra, Tilak; Zou, Xiang; Valente, Edward J.; Brown, Kenneth L. Journal of Organic Chemistry, 2006 , vol. 71, # 13 p. 5000 - 5003

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   0.5488
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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