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CS-W001157 4
Total: USD 88.00

Mizoribine

  • CAS No. 50924-49-7

  • Cat. No. CS-1823
  • Purity≥98%
  • MDL No.MFCD00057221

*For research and further manufacturing use only, not for direct human use.

Mizoribine|CS-1823

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General Information

  • CAS No. 50924-49-7
  • Cat. No. CS-1823
  • Purity ≥98%
  • MDL No. MFCD00057221
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃N₃O₆
  • Molecular Weight None
  • Synonym(s) NSC 289637; HE 69
  • SMILES OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(O)=C(C(N)=O)N=C2)O1

Description

Inhibiting IMP dehydrogenase activity, Mizoribine (CAS 50924-49-7) suppresses purine biosynthesis in activated T-cells, disrupting immune response propagation in autoimmune models.

Application

Mizoribine (CAS 50924-49-7) drives ocular surface protection in dry eye models by mitigating desiccating stress-induced damage in B6 mice. It potently inhibits IMPDH. Researchers leverage this mechanism to assess in vivo anti-inflammatory efficacy and evaluate therapeutic potential for chronic ocular surface disorders.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335-H360
Precautionary Statements : P233-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   151.06
  • LogP   -2.7009
  • H_Acceptors   8
  • H_Donors   5
  • Rotatable_Bonds   3

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